The Dynamic Duo: Transcription and DNA Damage

Motor proteins: A dynamic duo

The interactions between the microtubule motor cytoplasmic dynein and its putative regulator dynactin have been shown to be dynamic and complex.

Radiation track and DNA damage

The Dynamic Duo: Niche/Stem Cell Interdependency

Most tissues in our bodies undergo constant cellular turnover. This process requires a dynamic balance between cell production and elimination. Stem cells have been shown in many of these tissues to be the major source of new cells. However, despite the tremendous advances made, it still remains unclear how stem cell behavior and activity are regulated in vivo. Furthermore, we lack basic unders...

HGF and VEGF: a dynamic duo.

Copyright © 2005 American Heart Association. All rights reserved. Print ISSN: 0009-7330. Online TX 72514 Circulation Research is published by the American Heart Association. 7272 Greenville Avenue, Dallas, DOI: 10.1161/01.RES.0000157575.66295.e

Dynamic duo takes down fungal villains.

F ungal pathogens are notoriously difficult to treat because of antifungal drug toxicity and drug resistance, and the limited armamentarium (1). Some drug classes inhibit fungal growth but do not efficiently eliminate pathogens, and there is a pressing need for advances in antifungal therapy. The problem is especially acute in the immunocompromised. In a recent issue of PNAS, Cowen et al. (2) d...